衍生

Echolight

Echolight, Spin-off of the National Research Council set at the Lecce site of the Institute of Clinical Physiology, is a research-based hi-tech start-up specialized in the development of innovative medical devices for early diagnosis of osteoporosis.

The new developed echographic system, unique all over the world in its kind, exploits a revolutionary ultrasound technique for the assessment of bone strength at spine and femur level. Presently, the first phase of the clinical validation has been completed and an international multicenter study has been started.

Osteoporosis is a silent disease that affects more than 200 millions of women in the world, and the progressive population aging will increase the burden of the already alarming problem. Nevertheless, at present osteoporosis is still under-diagnosed, since the current gold standard technology is based on X-rays and therefore it is only available in hospital structures, with waiting lists up to two years.

Echolight will make available on the market the first device for early diagnosis of osteoporosis, so spreading the examination also to private practices and pharmacies for an effective diagnosis and prevention of the osteoporotic disease.

www.echolight.it

 Amolab

AMOLAB, Spin-off of the National Research Council, in Lecce, is a research based and high-tech company specialized in the development of innovative ultrasonic medical devices for the intrapartum assessment of labor progression indicators in a field with poor technological support and with alarming problems of clinical management.

Today, reliable and objective indications in the process of clinical decision towards surgical intervention (i.e., Caesarean Section) or an operative childbirth (i.e., application of forceps or vacuum extractor) are still lacking and relevant literature documents the high rates of errors (up to 88% of cases) in labor management. Additionally, in the obstetrics and gynecology clinical sector defensive medicine, medical litigations (insurance companies does not offer coverage to physicians) regarding human errors and risks for patients have reached unacceptable levels of social costs.

In Italy the average national rate of Cesarean Sections is 38% reaching 60% in some regions, and these values are continuously increasing with respect to the past decade (24% in Europe; 29% in the USA; 15% is the maximum rate recommended by WHO).

AMOLAB has developed a non-invasive ultrasound based method (patented at a national and international level) able to provide quantitative indications about labor progression and consequently, if necessary, directions about the applicability of different kinds of operative maneuvers and interventions.

www.amolab.it

Qualimedlab

I programmi di valutazione Esterna di Qualità in Medicina di Laboratorio (VEQ o EQAS External Quality Assessment Schemes) hanno lo scopo di permettere un confronto retrospettivo tra le determinazioni eseguite in laboratori differenti. I partecipanti ai programmi di VEQ ottengono, attraverso i rapporti periodici dei risultati, informazioni utili sulle prestazioni analitiche dei differenti metodi/kit utilizzati nelle misurazioni. QualiMedLab mette gratuitamente a disposizione dei laboratori interessati una VEQ DEMO che permette di testare le caratteristiche delle VEQ EQAS-CNR, senza bisogno di effettuare dosaggi.

www.qualimedlab.it

Quipu

Quipu srl è una società spin-off del Consiglio Nazionale delle Ricerche e dell'Università di Pisa, fondata da un gruppo di ingegneri e medici con una consolidata esperienza nel settore dell’ecografia. La missione di Quipu è di progettare una nuova generazione di sistemi a ultrasuoni basati su applicazioni software.

Quipu ha sviluppato una nuova piattaforma software che contiene applicazioni innovative per l’ecografia. La piattaforma gira su un personal computer standard e può essere connessa ad un qualsiasi scanner ad ultrasuoni esistente, aggiungendo funzioni avanzate ad una comune macchina ecografa. In una seconda fase di sviluppo, lo scanner ecografico potrà essere integrato come una periferica del computer così da completare una nuova architettura ecografica basata su applicazioni software.

Quipu ha completato e sta commercializzando le sue prime due applicazioni nel campo della prevenzione delle malattie cardiovascolari: (i) FMD Studio per la valutazione della funzione endoteliale tramite la misura della vasodilatazione fusso-mediata; (ii) Carotid Studio per la valutazione dello spessore e della rigidità carotidea nella valutazione precoce di aterosclerosi. Il prodotto software è un dispositivo medico CE (93/42/CEE).

www.quipu.eu

设施

IFC Pisamodel: Clinical model for predicting the probability of pulmonary embolism

When considered individually, symptoms, signs, or common laboratory tests have limited diagnostic power. Jointly, however, they may provide accurate assessment of the clinical probability of pulmonary embolism.

IFC developed two prediction models for the online computation of the clinical probability of pulmonary embolism.

The first evaluation model (PM1) is recommended to the physician skilled with the interpretation of the chest radiographs.
The second model (PM2) can be consulted in case of radiogram unavailability.

Software for PM1 PM2 can be downloaded for desktop, laptop, palm computers and mobile phones. 

References and contacts:

Simonetta Monti : 该 Email 地址已受到反垃圾邮件插件保护。要显示它需要在浏览器中启用 JavaScript。

EchoCardio-Norm

EchoCardio-Norm 是心脏病医生，心脏超声图专家，麻醉师，放射学专家的一个必要的简 单工具：是智能手机，平板电脑，台式电脑的应用程序，可以天天使用，计算正常心脏超声 图的数据。

此应用程序最大的创新是： 1) 可以立刻获得不同来源的正常资料，2)可以自动选择一个最适 当本体的参考价值，以年龄，性别及种族为基础。

有关心脏磁共振成像的特别部分内，有一段专为正态范围而设。

此应用程序可用在Android 智能手机及个人电脑，操作系统 是OSX 及 LINUX。

EchoCardio-Norm是与两间意大利机构 ：Fondazione Toscana G. Monastero FTGM, 及IFCCNR 合作来发展的。

• UNIX 版本:  https://box.ifc.cnr.it/index.php/s/kaaCU0H3XQPmViP
  

• OSX 版本:  https://box.ifc.cnr.it/index.php/s/wOPOgrsDlExTA80

• Windows 版本: https://box.ifc.cnr.it/index.php/s/t6uYFocpFId41aZ
  

SORTER-ò

FACS 荧光激活细胞分选术是用来分开有不同特征的但共存在同一异源种群的细胞的技术。 相关的细胞以一个或几个荧光团来标记（由适当的矢量来表达的荧光蛋白质如GFP 或 RFP，能认出特殊薄膜蛋白质，有特别酶活性的荧光产品，插入DNA的荧光分子的荧光抗 体），然后跟种群其它部分分开。FACS的基本益处是分选得到的细胞是活体细胞，可以用 来研究它们的生物特性，以及表型特征。故此这分选术应用在不同研究范围：在心血管生物 学用来研究内皮细胞的区分，在发展生物学用来研究心脏及中央神经系统的成型，在癌症生 物学用来研究癌细胞的异源种群。 [Read more]

比萨地区（也不单只比萨）的研究人员一直缺少了细胞分选仪，这给他们造成不少困难，为 了弥补这缺憾，IFC 及Istituto Toscano Tumori 及其它附属CNR的机构（神经科学学院， 生 物物理学院，生物医学技术学院，遗传学及生物医学研究学院）共同努力在S. Cataldo研究 区安装了细胞分选仪FACSJazz BD， 有两架激光器 （488 nm 及 561 nm），让有超过10年 的流式细胞仪经验的技术专业人员使用及维修，不少科学刊物都有点出。

在一专业技术人员的监督下使用分选仪，技术人员维修设备及施行相关实验。

服务包括:

• 协助分选程序实验的调定
• 协助获得，分析及 理解资料
• 协助资料报告

The conditions and technical details of this service are described as follows:

The FACSjazz instrument available at IFC

Access form to the sorting service available at IFC

IFC Sorting Facility-Booking Form